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Biochemistry

Senior Scientist, Cell Line Development

Bioprocess Engineer

Associate Director of Bioprocess Development


 

 

 

 

 

Associate Director of Bioprocess Development


A pharmaceutical company located in New York is seeking an Associate Director of Bioprocess Development who will have the overall responsibility for the department and its staff of approximately 20-25 scientific and engineering professionals. Responsibilities include oversight of technical groups responsible for the development of biologics manufacturing processes. The Associate Director, Bioprocess Development will report to the Director of Biotechnology Development. He or she should have solid demonstrated leadership qualities and be results oriented. He or she will be an innovative, visionary and strategic individual with a drive for continuous improvement. Additional attributes desired include superior intelligence, sound judgment, high energy, a strong work ethic, flexibility, motivational and empowerment skills and dedication.
Specific responsibilities will include providing tactical and strategic oversight to the Bioprocess Development group and leadership in the linkages with Quality Operations, Bioprocess Engineering, Development Support, and Biotechnology Operations. The Associate Director will also be responsible for the recruiting, retention and development of talent in the Bioprocess Development organization; the development and alignment of objectives with partner organizations; and maintaining relationships with internal and external partners involved in Bioprocess Development projects.
Position Requirements:
The ideal candidate will have a Ph.D. in biochemical engineering or a relevant biological science, strong academic credentials, a solid history of technical accomplishments with at least 5 years of industrial experience in biotechnology and successful, demonstrated supervisory experience. Specific qualifications desired include a demonstrated knowledge of biologic manufacturing processes and process science, and demonstrated skills in budget management.

 

 

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Bioprocess Engineer

 

A pharmaceutical company located in New York is seeking an Engineer who will be engaged in process development and process improvement activities for the downstream processing of innovative late stage biological molecules as a member of the purification group. The successful candidate will possess extensive skills in chromatography including ion exchange, hydrophobic interaction, affinity and HPLC, filtration including microfiltration and ultrafiltration and electrophoresis including SDS PAGE, IEF and western blots. The successful candidate will also have extensive protein chromatography, protein chemistry and mathematical skills. The engineer will provide technical support for downstream operations, process validation and Technical Services and will provide laboratory scale support as needed. The successful candidate will interface with operations, validation, analytical and quality assurance personnel to enhance the performance of commercial scale production operations.

Requirements:
The successful candidate will have a Ph.D. in a Biochemistry or Chemical Engineering program with 0 to 5 years of relevant industrial experience. The candidate will also have a demonstrated record of experience in chromatography and or filtration and multiple peer reviewed publications and external presentations. Effective communication skills in a technical environment are required. The candidate also must be able to perform as a member of a scientific team. Supervisory experience is recommended.

 

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Senior Scientist, Cell Line Development


A pharmaceutical company located in New York is seeking Senior Scientist, Cell Line Development for a technical leadership position responsible for cell line development, cell line screening and media optimization for the manufacture of biologic products. Candidate will provide technical oversight for cell line development and media optimization projects within Biotechnology Development. Candidate will be expected to establish active collaborations within Biotechnology Development and with partner groups, including Analytical Biochemistry, Biologics Quality and Operations. Candidate will also be responsible for developing innovative approaches to the development of manufacturing cell lines. This position is responsible for maintaining state of the art knowledge in appropriate scientific disciplines, especially in the area in which he or she is working, through published literature and attendance at internal and external scientific meetings.

Requirements:
The successful candidate will have a Ph.D. in Molecular Genetics, Biochemistry, or a related field. Must have demonstrated experience in the development of mammalian cell lines. Effective written and verbal communication skills required. Experience with monoclonal antibodies or fusion proteins desirable.

 

 

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